Goiter symptoms include: Neck Swelling: Enlargement or apparent swelling at the front of the neck. Difficulty Swallowing symptoms include a lump or pressure in the throat. Hoarseness: Vocal changes or persistent hoarseness. Breathing Difficulties: Difficulty breathing or shortness of breath in extreme situations. Coughing: A persistent or chronic cough is possible. Tightness or Pain: Neck discomfort or pain. Throat Irritation: A burning or itching sensation in the throat.