Symptoms of hormone imbalance can vary depending on which hormones are affected and the individual's unique physiology. Some common symptoms are: Menstrual periods are irregular. Mood swings or mood shifts. Gaining weight or having difficulties shedding it. Fatigue and poor energy levels. Insomnia or sleep disturbance. Libido or sexual function changes. Hot flashes or night sweats. Hair loss or thinning. Skin problems such as acne or dry skin. Bloating, constipation, and other digestive disorders. Memory impairment or difficulty concentrating. Muscular weakness or pains. Changes in appetite or food cravings. Temperature sensitivity.